The Up-regulation of TNF-α Maintains Trigeminal Neuralgia by Modulating MAPKs Phosphorylation and BKCa Channels in Trigeminal Nucleus Caudalis

Trigeminal neuralgia (TN) is a severe chronic neuropathic pain. Despite numerous available medical interventions, the therapeutic effects are not ideal. To control the pain attacks, the need for more contemporary drugs continues to be a real challenge. Our previous study reported that Ca2+-activated...

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Principais autores:	Zhan-ying Lu, Juan Fan, Li-hua Yu, Bei Ma, Li-ming Cheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-11-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	trigeminal neuralgia TNF-α trigeminal nucleus caudalis MAPKs phosphorylation BKCa channel
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fncel.2021.764141/full
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