PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

ABSTRACT Migraine is a prevalent and debilitating neurological disorder with poorly understood neural mechanisms. Here, we characterize a hypothalamic‐trigeminal pathway involved in the regulation of migraine‐like allodynia. Using a combination of monosynaptic circuit, fiber photometry‐based calcium...

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Autori principali:	Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-05-01
Serie:	Advanced Science
Soggetti:	chronic migraine corticotropin‐releasing factor the hypothalamic paraventricular nucleus the spinal trigeminal nucleus caudalis
Accesso online:	https://doi.org/10.1002/advs.202520530
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