In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature

Abstract Background Cardioprotective value of ischemic post- (IPostC), remote (RIC) conditioning in acute myocardial infarction (AMI) is unclear in clinical trials. To evaluate cardioprotection, most translational animal studies and clinical trials utilize necrotic tissue referred to the area at ris...

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Hauptverfasser:	Tamás Baranyai, Zoltán Giricz, Zoltán V. Varga, Gábor Koncsos, Dominika Lukovic, András Makkos, Márta Sárközy, Noémi Pávó, András Jakab, Csilla Czimbalmos, Hajnalka Vágó, Zoltán Ruzsa, Levente Tóth, Rita Garamvölgyi, Béla Merkely, Rainer Schulz, Mariann Gyöngyösi, Péter Ferdinandy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2017-04-01
Schriftenreihe:	Journal of Translational Medicine
Schlagworte:	Ischemic preconditioning Ischemic postconditioning Remote conditioning Myocardial edema Area at risk Ischemia/reperfusion injury
Online-Zugang:	http://link.springer.com/article/10.1186/s12967-017-1166-z
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