Rosiglitazone Promotes AQP2 Plasma Membrane Expression In Renal Cells Via a Ca2+-Dependent/cAMP-Independent Mechanism

Background/Aims: Thiazolidinediones are highly beneficial in the treatment of type II diabetes. However, they are also associated with edema and increased risk of congestive heart failure. Several studies demonstrated that rosiglitazone (RGZ) increases the abundance of aquaporin-2 (AQP2) at the plas...

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Detalhes bibliográficos

Principais autores:	Giuseppe Procino, Andrea Gerbino, Serena Milano, Maria Celeste Nicoletti, Lisa Mastrofrancesco, Monica Carmosino, Maria Svelto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
coleção:	Cellular Physiology and Biochemistry
Assuntos:	Edema Aquaporin 2 Vasopressin Thiazolidinediones Rosiglitazone Calcium signaling Transient receptor potential
Acesso em linha:	http://www.karger.com/Article/FullText/373933
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