EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans

Ephrin receptors constitute a large family of receptor tyrosine kinases in mammals that through interaction with cell surface-anchored ephrin ligands regulate multiple different cellular responses in numerous cell types and tissues. In the cardiovascular system, studies performed in vitro and in viv...

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Príomhchruthaitheoirí:	Di Chen, Martijn A. Van der Ent, Nathaniel L. Lartey, Philip D. King
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	MDPI AG 2023-01-01
Sraith:	Pharmaceuticals
Ábhair:	Ephrin receptor B4 RASA1 Ras-MAPK pathway capillary malformation arteriovenous malformation lymphatic malformation angiogenesis
Rochtain ar líne:	https://www.mdpi.com/1424-8247/16/2/165
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