The cellular prion protein: a player in immunological quiescence

Despite intensive studies since the 1990s, the physiological role of the cellular prion protein (PrPC) remains elusive. Here, we present a novel concept suggesting that PrPC contributes to immunological quiescence in addition to cell protection. PrPC is highly expressed in diverse organs that by mul...

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Bibliografske podrobnosti

Principais autores:	Maren Kolltveit Bakkebø, Sophie eMouillet-Richard, Arild Espenes Espenes, Wilfred eGoldmann, Jörg eTatzelt, Michael Andreas Tranulis
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2015-09-01
Serija:	Frontiers in Immunology
Teme:	Cytoprotection Inflammation Alzheimer prion protein neurodegeneration Cell signaling
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00450/full
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