Goats naturally devoid of PrPC are resistant to scrapie
Abstract Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the “protein-only” hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological and infectious form (PrPSc) in these diseases. Transgenic knockout...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-01-01
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| coleção: | Veterinary Research |
| Acesso em linha: | https://doi.org/10.1186/s13567-019-0731-2 |
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