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Synthesis and preclinical development of a novel 68Ga/89Zr-Labelled ανβ6-integrin targeting trimer

Abstract Background The αvβ6 integrin has emerged as a valuable target for theranostic applications in nuclear medicine with high applicability across a variety of cancers, including head-and-neck, lung, breast, and pancreatic carcinomas. [⁶⁸Ga]Ga-Trivehexin is a prominent example of a diagnostic tr...

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Principais autores: Giacomo Gariglio, Fernando A Patiño Álvarez, Maximilian A Zierke, Stefan Stangl, Tim Rheinfrank, Nadine Holzleitner, Susanne Kossatz, Clemens Decristoforo
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-02-01
Serier:EJNMMI Radiopharmacy and Chemistry
Fag:
Integrin
PET imaging
Fusarinine C
Gallium-68
Zirconium-89
Online adgang:https://doi.org/10.1186/s41181-025-00423-x
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