Modified poly-L-lysine for use as a clearing agent in pretargeted radioimmunotherapy

Abstract Background Pretargeted radioimmunotherapy of cancer has the potential to increase tumor specific uptake of activity when compared with conventional radioimmunotherapy. This is especially true in radioimmunotherapy with nuclides that exhibit a relatively short half-life. When administering a...

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Hlavní autoři:	Chiara Timperanza, Anna Gustafsson-Lutz, Tom Bäck, Damian J. Green, Sture Lindegren, Emma Aneheim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	SpringerOpen 2024-11-01
Edice:	EJNMMI Radiopharmacy and Chemistry
Témata:	Pretargeted radioimmunotherapy Pretargeting Clearing agent Poly-L-lysine Streptavidin/avidin–biotin Tetrazine-Transcyclooctene/TCO, Click chemistry
On-line přístup:	https://doi.org/10.1186/s41181-024-00307-6
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