Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane
Human YME1L is a membrane-anchored AAA+ protease that maintains proteostasis in the mitochondrial inner membrane and intermembrane space. Here the authors probe the substrate-binding and degradation activities of YME1L and suggest the existence of sequence-specific degradation signals in mitochondri...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2016-10-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/ncomms13301 |
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