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Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane

Human YME1L is a membrane-anchored AAA+ protease that maintains proteostasis in the mitochondrial inner membrane and intermembrane space. Here the authors probe the substrate-binding and degradation activities of YME1L and suggest the existence of sequence-specific degradation signals in mitochondri...

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書誌詳細
主要な著者: Hui Shi, Anthony J. Rampello, Steven E. Glynn
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2016-10-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/ncomms13301
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