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A P2RY12 deficiency results in sex-specific cellular perturbations and sexually dimorphic behavioral anomalies

Abstract Microglia are sexually dimorphic, yet, this critical aspect is often overlooked in neuroscientific studies. Decades of research have revealed the dynamic nature of microglial-neuronal interactions, but seldom consider how this dynamism varies with microglial sex differences, leaving a signi...

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Principais autores: Ogochukwu J. Uweru, Akhabue K. Okojie, Aparna Trivedi, Jordan Benderoth, Lauren S. Thomas, Georgia Davidson, Kendall Cox, Ukpong B. Eyo
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-04-01
Series:Journal of Neuroinflammation
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Acceso en liña:https://doi.org/10.1186/s12974-024-03079-7
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