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Acetylation and accessibility of Cryptococcus neoformans cell wall chitosans influence the strength of host immune responses

The fungal pathogen Cryptococcus neoformans causes fatal cryptococcal meningitis, a significant global health risk. Unlike most fungi, C. neoformans expresses chitin deacetylases that convert its cell wall chitin into chitosan, helping to evade chitin-triggered host immunity. However, it is unclear...

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Autori principali: Margareta J. Hellmann, Rajendra Upadhya, Evelyn Tchoub, Bruno M. Moerschbacher, Jennifer K. Lodge, Stefan Cord-Landwehr
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-06-01
Serie:The Cell Surface
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2468233026000083
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