Membrane Integrity Contributes to Resistance of Cryptococcus neoformans to the Cell Wall Inhibitor Caspofungin

ABSTRACT The fungal pathogen Cryptococcus neoformans causes up to 278 000 infections each year globally, resulting in up to 180,000 deaths annually, mostly impacting immunocompromised people. Therapeutic options for C. neoformans infections are very limited. Caspofungin, a member of the echinocandin...

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Hlavní autoři:	Brenda Moreira-Walsh, Abigail Ragsdale, Woei Lam, Rajendra Upadhya, Evan Xu, Jennifer K. Lodge, Maureen J. Donlin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2022-08-01
Edice:	mSphere
Témata:	antifungal agents antifungal resistance Cryptococcus neoformans fungal cell wall
On-line přístup:	https://journals.asm.org/doi/10.1128/msphere.00134-22
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