Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain.
Proteins bearing a leucine-rich nuclear export signal (NES) are exported from the nucleus by the transport factor CRM1, which forms a cooperative ternary complex with the NES-bearing cargo and with the small GTPase Ran. CRM1-mediated export is regulated by RanBP3, a Ran-interacting nuclear protein....
Uloženo v:
| Hlavní autoři: | , , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2011-02-01
|
| Edice: | PLoS ONE |
| On-line přístup: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017011&type=printable |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|