Defining early changes in Alzheimer’s disease from RNA sequencing of brain regions differentially affected by pathology
Abstract Tau pathology in Alzheimer’s disease (AD) spreads in a predictable pattern that corresponds with disease symptoms and severity. At post-mortem there are cortical regions that range from mildly to severely affected by tau pathology and neuronal loss. A comparison of the molecular signatures...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2021-03-01
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| Serija: | Scientific Reports |
| Online dostop: | https://doi.org/10.1038/s41598-021-83872-z |
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