Efficient and specific generation of knockout mice using Campylobacter jejuni CRISPR/Cas9 system
The Streptococcus pyogenes CRISPR/Cas9 (SpCas9) system is now widely utilized to generate genome engineered mice; however, some studies raised issues related to off-target mutations with this system. Herein, we utilized the Campylobacter jejuni Cas9 (CjCas9) system to generate knockout mice. We desi...
שמור ב:
| Principais autores: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2020-07-01
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| סדרה: | Biochemistry and Biophysics Reports |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2405580820300613 |
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