CRISPR/Cas9-mediated knockout of clinically relevant alloantigenes in human primary T cells
Abstract Background The ability of CRISPR/Cas9 to mutate any desired genomic locus is being increasingly explored in the emerging area of cancer immunotherapy. In this respect, current efforts are mostly focused on the use of autologous (i.e. patient-derived) T cells. The autologous approach, howeve...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2021-01-01
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| coleção: | BMC Biotechnology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12896-020-00665-4 |
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