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Application of codon usage and context analysis in genes up- or down-regulated in neurodegeneration and cancer to combat comorbidities

IntroductionNeurodegeneration and cancer present in comorbidities with inverse effects due to the expression of genes and pathways acting in opposition. Identifying and studying the genes simultaneously up or downregulated during morbidities helps curb both ailments together.MethodsThis study examin...

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Principais autores: Rekha Khandia, Megha Katare Pandey, Magdi E. A. Zaki, Sami A. Al-Hussain, Igor Baklanov, Pankaj Gurjar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-06-01
coleção:Frontiers in Molecular Neuroscience
Assuntos:
codon usage
codon pattern
synonymous codons
neurodegeneration
cancer
CRISPR/Cas
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1200523/full
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