Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of <i>ACE2</i> in Diabetic Donors

Cellular entry of SARS-CoV-2 is thought to occur through the binding of viral spike S1 protein to <i>ACE2</i>. The entry process involves priming of the S protein by <i>TMPRSS2</i> and <i>ADAM17</i>, which collectively mediate the binding and promote ACE2 shedding. In this study, microarray and RNA-...

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Principais autores:	Jalal Taneera, Waseem El-Huneidi, Mawieh Hamad, Abdul Khader Mohammed, Esraa Elaraby, Mahmood Yaseen Hachim
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2020-08-01
סדרה:	Biology
נושאים:	COVID-19 Diabetes human islets <i>ACE2</i> <i>ADAM17</i> <i>TMPRSS2</i>
גישה מקוונת:	https://www.mdpi.com/2079-7737/9/8/215
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!