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Network Pharmacology Analysis, Molecular Docking Integrated Experimental Verification Reveal the Mechanism of <i>Gynostemma pentaphyllum</i> in the Treatment of Type II Diabetes by Regulating the IRS1/PI3K/Akt Signaling Pathway

<i>Gynostemma pentaphyllum</i> (Thunb.) Makino (GP), a plant with homology of medicine and food, as a traditional Chinese medicine, possesses promising biological activities in the prevention and treatment of type 2 diabetes mellitus (T2DM). However, the material basis and the mechanism of action of...

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Huvudupphov: Songqin Yang, Mao Zhao, Mingxing Lu, Yuhan Feng, Xia Zhang, Daoping Wang, Wenwen Jiang
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2024-06-01
Serie:Current Issues in Molecular Biology
Ämnen:
type 2 diabetes
<i>Gynostemma pentaphyllum</i> (Thunb.) Makino
insulin resistance
network pharmacology
molecular docking
PI3K/Akt signaling pathway
Länkar:https://www.mdpi.com/1467-3045/46/6/333
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