Network Pharmacology Analysis, Molecular Docking Integrated Experimental Verification Reveal the Mechanism of <i>Gynostemma pentaphyllum</i> in the Treatment of Type II Diabetes by Regulating the IRS1/PI3K/Akt Signaling Pathway

<i>Gynostemma pentaphyllum</i> (Thunb.) Makino (GP), a plant with homology of medicine and food, as a traditional Chinese medicine, possesses promising biological activities in the prevention and treatment of type 2 diabetes mellitus (T2DM). However, the material basis and the mechanism of action of...

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Detalles Bibliográficos

Principais autores:	Songqin Yang, Mao Zhao, Mingxing Lu, Yuhan Feng, Xia Zhang, Daoping Wang, Wenwen Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-06-01
Series:	Current Issues in Molecular Biology
Assuntos:	type 2 diabetes <i>Gynostemma pentaphyllum</i> (Thunb.) Makino insulin resistance network pharmacology molecular docking PI3K/Akt signaling pathway
Acceso en liña:	https://www.mdpi.com/1467-3045/46/6/333
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