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Population variability in X-chromosome inactivation across 10 mammalian species

Abstract One of the two X-chromosomes in female mammals is epigenetically silenced in embryonic stem cells by X-chromosome inactivation. This creates a mosaic of cells expressing either the maternal or the paternal X allele. The X-chromosome inactivation ratio, the proportion of inactivated parental...

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Bibliografiske detaljer
Principais autores: Jonathan M. Werner, John Hover, Jesse Gillis
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-10-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-024-53449-1
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