Chromosomal Variation and the Origin of Drug-Resistant Mutants in Mammalian Cell Lines
Drug-resistant mutants of somatic cell lines fall into two classes: one seems to correspond to classical gene mutation, the other is characterized, albeit transiently, by karyotypic instability, high reversion frequency, and low plating efficiency. An interpretation of the origin of these drug-resis...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1974
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4531035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.5027 |
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