Iron as a Therapeutic Target in <i>HFE</i>-Related Hemochromatosis: Usual and Novel Aspects
Genetic hemochromatosis is an iron overload disease that is mainly related to the <i>C282Y</i> mutation in the <i>HFE</i> gene. This gene controls the expression of hepcidin, a peptide secreted in plasma by the liver and regulates systemic iron distribution. Homozygous <i>C282Y</i> mutation induces...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2018-11-01
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| coleção: | Pharmaceuticals |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1424-8247/11/4/131 |
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