Iron as a Therapeutic Target in <i>HFE</i>-Related Hemochromatosis: Usual and Novel Aspects
Genetic hemochromatosis is an iron overload disease that is mainly related to the <i>C282Y</i> mutation in the <i>HFE</i> gene. This gene controls the expression of hepcidin, a peptide secreted in plasma by the liver and regulates systemic iron distribution. Homozygous <i>C282Y</i> mutation induces...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2018-11-01
|
| Schriftenreihe: | Pharmaceuticals |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/1424-8247/11/4/131 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|