Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.

The contribution of pre-mRNA processing mechanisms to the regulation of immune responses remains poorly studied despite emerging examples of their role as regulators of immune defenses. We sought to investigate the role of mRNA processing in the cellular responses of human macrophages to live bacter...

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Detalhes bibliográficos

Principais autores:	Athma A Pai, Golshid Baharian, Ariane Pagé Sabourin, Jessica F Brinkworth, Yohann Nédélec, Joseph W Foley, Jean-Christophe Grenier, Katherine J Siddle, Anne Dumaine, Vania Yotova, Zachary P Johnson, Robert E Lanford, Christopher B Burge, Luis B Barreiro
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2016-09-01
coleção:	PLoS Genetics
Acesso em linha:	http://europepmc.org/articles/PMC5045211?pdf=render
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