Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression

<p>Abstract</p> <p>Background</p> <p>NOD2 is an innate immune receptor for the bacterial cell wall component muramyl-dipeptide. Mutations in the leucine-rich repeat region of NOD2, which lead to an impaired recognition of muramyl-dipeptide, have been associated with Crohn disease, a human chronic in...

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Detalhes bibliográficos

Principais autores:	Mathew Christopher G, Roberts Roland G, Platzer Cornelia, Reichwald Kathrin, Hampe Jochen, Franke Andre, Huse Klaus, Rosenstiel Philip, Platzer Matthias, Schreiber Stefan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2007-12-01
coleção:	BMC Genomics
Acesso em linha:	http://www.biomedcentral.com/1471-2164/8/472
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