Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.

Previously, a candidate gene linkage approach on brother pairs affected with prostate cancer identified a locus of prostate cancer susceptibility at D3S1234 within the fragile histidine triad gene (FHIT), a tumor suppressor that induces apoptosis. Subsequent association tests on 16 SNPs spanning app...

Descripció completa

Dades bibliogràfiques

Autors principals:	Yan Ding, Garrett Larson, Guillermo Rivas, Cathryn Lundberg, Louis Geller, Ching Ouyang, Jeffrey Weitzel, John Archambeau, Jerry Slater, Mary B Daly, Al B Benson, John M Kirkwood, Peter J O'Dwyer, Rebecca Sutphen, James A Stewart, David Johnson, Magnus Nordborg, Theodore G Krontiris
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2008-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://doi.org/10.1371/journal.pone.0003533
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!