Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.

Previously, a candidate gene linkage approach on brother pairs affected with prostate cancer identified a locus of prostate cancer susceptibility at D3S1234 within the fragile histidine triad gene (FHIT), a tumor suppressor that induces apoptosis. Subsequent association tests on 16 SNPs spanning app...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yan Ding, Garrett Larson, Guillermo Rivas, Cathryn Lundberg, Louis Geller, Ching Ouyang, Jeffrey Weitzel, John Archambeau, Jerry Slater, Mary B Daly, Al B Benson, John M Kirkwood, Peter J O'Dwyer, Rebecca Sutphen, James A Stewart, David Johnson, Magnus Nordborg, Theodore G Krontiris
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Public Library of Science (PLoS) 2008-01-01
Sarja:	PLoS ONE
Linkit:	https://doi.org/10.1371/journal.pone.0003533
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