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Human aldo-keto reductases: structure, substrate specificity and roles in tumorigenesis

The aldo-keto reductase (AKR) superfamily consists of over 150 protein members sharing similar structure and enzymatic activities. To date, 13 human AKRs have been identified, and they participate in xenobiotic detoxification, biosynthesis and metabolism. Increasing evidence suggests the involvement...

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Bibliografiske detaljer
Principais autores: Ma Jun, Cao Deliang
Format: Artigo
Sprog:Inglês
Udgivet: De Gruyter 2011-04-01
Serier:Biomolecular Concepts
Fag:
Online adgang:https://doi.org/10.1515/bmc.2011.010
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