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Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development

Abstract After menstruation the uterine spiral arteries are repaired through angiogenesis. This process is tightly regulated by the paracrine communication between endometrial stromal cells (EnSCs) and endothelial cells. Any molecular aberration in these processes can lead to complications in pregna...

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Sparad:
Huvudupphov: Janet P. Raja Xavier, Toshiyuki Okumura, Melina Apweiler, Nirzari A. Chacko, Yogesh Singh, Sara Y Brucker, Satoru Takeda, Florian Lang, Madhuri S Salker
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2024-08-01
Serie:Biological Research
Ämnen:
PlGF
Endometrium
Placentation
Pregnancy
Preeclampsia
SGK1
Länkar:https://doi.org/10.1186/s40659-024-00526-w
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