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Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development

Abstract After menstruation the uterine spiral arteries are repaired through angiogenesis. This process is tightly regulated by the paracrine communication between endometrial stromal cells (EnSCs) and endothelial cells. Any molecular aberration in these processes can lead to complications in pregna...

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Principais autores: Janet P. Raja Xavier, Toshiyuki Okumura, Melina Apweiler, Nirzari A. Chacko, Yogesh Singh, Sara Y Brucker, Satoru Takeda, Florian Lang, Madhuri S Salker
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:Biological Research
Fag:
PlGF
Endometrium
Placentation
Pregnancy
Preeclampsia
SGK1
Online adgang:https://doi.org/10.1186/s40659-024-00526-w
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