Immune checkpoint blockade induces distinct alterations in the microenvironments of primary and metastatic brain tumors

In comparison with responses in recurrent glioblastoma (rGBM), the intracranial response of brain metastases (BrM) to immune checkpoint blockade (ICB) is less well studied. Here, we present an integrated single-cell RNA-Seq (scRNA-Seq) study of 19 ICB-naive and 9 ICB-treated BrM samples from our own...

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מידע ביבליוגרפי

Principais autores:	Lu Sun, Jenny C. Kienzler, Jeremy G. Reynoso, Alexander Lee, Eileen Shiuan, Shanpeng Li, Jiyoon Kim, Lizhong Ding, Amber J. Monteleone, Geoffrey C. Owens, Joanna J. Phillips, Richard G. Everson, David Nathanson, Timothy F. Cloughesy, Gang Li, Linda M. Liau, Willy Hugo, Won Kim, Robert M. Prins
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical Investigation 2023-09-01
סדרה:	The Journal of Clinical Investigation
נושאים:	Immunology Neuroscience
גישה מקוונת:	https://doi.org/10.1172/JCI169314
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!