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Gastric cancer cell-derived exosomal miR-541-5p induces M2 macrophage polarization through DUSP3/JAK2/STAT3 pathway

Abstract Purpose Exosomal microRNAs have been identified as important mediators of communication between tumor cells and macrophages in the microenvironment. miR-541-5p was reported to be involved in hepatocellular carcinoma progression, but its role in gastric cancer (GC) and in GC cell-macrophage...

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Principais autores: Haimin Xiao, Jia Fu, Ruiting Liu, Likun Yan, Zheqi Zhou, Jinyan Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-08-01
coleção:BMC Cancer
Assuntos:
Gastric cancer
Exosome
miR-541-5p
Macrophage polarization
DUSP3
JAK2/STAT3 pathway
Acesso em linha:https://doi.org/10.1186/s12885-024-12672-1
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