Knockdown of liver cancer cell‐secreted exosomal PSMA5 controls macrophage polarization to restrain cancer progression by blocking JAK2/STAT3 signaling

Abstract Introduction Tumor‐associated macrophages, a major component of the tumor microenvironment, undergo polarization into M2 macrophages (M2), and thereby exert an immunosuppressive effect to induce cancer metastasis. This study strives to uncover a molecular mechanism underlying this event in...

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Detaylı Bibliyografya

Asıl Yazarlar:	Shujie Xie, Xiang Li, Jia Yan, Hua Yu, Shuhuai Chen, Kana Chen
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Wiley 2024-02-01
Seri Bilgileri:	Immunity, Inflammation and Disease
Konular:	exosomes hepatocellular carcinoma JAK2/STAT3 signaling M2 macrophage PSMA5
Online Erişim:	https://doi.org/10.1002/iid3.1146
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