Endogenous Retrovirus-Derived Long Noncoding RNA Enhances Innate Immune Responses via Derepressing RELA Expression

ABSTRACT Endogenous retroviruses (ERVs) are transposable elements that cause host genome instability and usually play deleterious roles in disease such as tumorigenesis. Recent advances also suggest that this “enemy within” may encode a viral mimic to induce antiviral immune responses through viral...

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Manylion Llyfryddiaeth

Prif Awduron:	Bin Zhou, Fei Qi, Fangyi Wu, Hongbo Nie, Yifan Song, Lu Shao, Jingxuan Han, Zhen Wu, Hexige Saiyin, Gang Wei, Penghua Wang, Ting Ni, Feng Qian
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology 2019-08-01
Cyfres:	mBio
Pynciau:	NF-κB antiviral immune responses endogenous retroviruses gene regulation lncRNA
Mynediad Ar-lein:	https://journals.asm.org/doi/10.1128/mBio.00937-19
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!