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The cell biology of HIV-1 latency and rebound

Abstract Transcriptionally latent forms of replication-competent proviruses, present primarily in a small subset of memory CD4+ T cells, pose the primary barrier to a cure for HIV-1 infection because they are the source of the viral rebound that almost inevitably follows the interruption of antiretr...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Uri Mbonye, Jonathan Karn
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-04-01
Schriftenreihe:Retrovirology
Schlagworte:
Online-Zugang:https://doi.org/10.1186/s12977-024-00639-w
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