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Identification of driver genes based on gene mutational effects and network centrality

Abstract Background As one of the deadliest diseases in the world, cancer is driven by a few somatic mutations that disrupt the normal growth of cells, and leads to abnormal proliferation and tumor development. The vast majority of somatic mutations did not affect the occurrence and development of c...

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Principais autores: Yun-Yun Tang, Pi-Jing Wei, Jian-ping Zhao, Junfeng Xia, Rui-Fen Cao, Chun-Hou Zheng
格式: Artigo
语言:Inglês
出版: BMC 2021-09-01
丛编:BMC Bioinformatics
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在线阅读:https://doi.org/10.1186/s12859-021-04377-0
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