Dynamic functional assessment of T cells reveals an early suppression correlating with adverse outcome in polytraumatized patients

IntroductionMost trauma patients require intensive care treatment and are susceptible to developing persistent inflammation and immunosuppression, potentially leading to multi organ dysfunction syndrome (MODS) and dependence on long term care facilities. T cells undergo changes in numbers and functi...

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Principais autores:	Tobias Jooss, Katharina Maier, Lena-Marie Reichardt, Bianca Hindelang, Lönna Süberkrüb, Kim Lena Hamberger, Jasmin Maria Bülow, Konrad Schuetze, Florian Gebhard, Marco Mannes, Rebecca Halbgebauer, Lisa Wohlgemuth, Markus Huber-Lang, Borna Relja, Christian B. Bergmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-03-01
Colecção:	Frontiers in Immunology
Assuntos:	trauma immunomonitoring T cells interferon gamma CD8 T cells prediction
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1538516/full
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