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Monitoring ctDNA RAS Mutational Status in Metastatic Colorectal Cancer: A Trial Protocol of RAS-trace and RAS-trace-2 Studies

Background: Spatial and temporal heterogeneities of RAS and other molecular genes should be considered in the treatment of metastatic colorectal cancer (mCRC) treated with anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs); acquired RAS mutation is sometimes observed at diseas...

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Principais autores: Kozo Kataoka, Takeshi Yamada, Manabu Shiozawa, Naoto Takase, Kazuma Ito, Kentaro Yamazaki, Jun Watanabe, Toshihiro Kudo, Takeshi Suto, Toshihiko Matsumoto, Kohei Murata, Yusuke Suwa, Shogen Boku, Hisateru Yasui, Nobuhisa Matsuhashi, Atsuyuki Maeda, Kiichi Sugimoto, Yusuke Matsumoto, Mitsuru Yokota, Johannes Fredebohm, Keita Mori, Masataka Ikeda
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Society of Coloproctology 2024-04-01
coleção:Journal of the Anus, Rectum and Colon
Assuntos:
colorectal cancer
anti-egfr monoclonal antibody
ras-trace
ras-trace-2
ctdna
Acesso em linha:https://www.jstage.jst.go.jp/article/jarc/8/2/8_2023-051/_pdf/-char/en
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