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Immune-oncology targets and therapeutic response of cell pyroptosis-related genes with prognostic implications in neuroblastoma

Abstract Objective Construction of a neuroblastoma (NB) prognostic predictive model based on pyroptosis-related genes (PRGs) to improve individualized management of NB patients. Methods The NB cohort GSE49711 was obtained from the Gene Expression Omnibus (GEO) database, and a total of 498 patients w...

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Main Authors: Xingyu Liu, Zhongya Xu, Hanjun Yin, Xu Zhao, Jinjiang Duan, Kai Zhou, Qiyang Shen
Format: Artigo
Language:Inglês
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
Neuroblastoma
Pyroptosis
Immune microenvironment
Prognostic model
Nomogram
Online Access:https://doi.org/10.1007/s12672-024-01518-8
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