A natural hydrogel complex improves intervertebral disc degeneration by correcting fatty acid metabolism and inhibiting nucleus pulposus cell pyroptosis

The degeneration of intervertebral discs is strongly associated with the occurrence of pyroptosis in nucleus pulposus (NP) cells. This pyroptosis is characterized by abnormal metabolism of fatty acids in the degenerative pathological state, which is further exacerbated by the inflammatory microenvir...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Dong Wang, Liangping Zhang, Du He, Yujun Zhang, Lan Zhao, Zhimin Miao, Wei Cheng, Chengyue Zhu, Yinyan Shao, Guofen Ge, Hang Zhu, HongTing Jin, Wei Zhang, Hao Pan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-06-01
Schriftenreihe:	Materials Today Bio
Schlagworte:	Intervertebral disc degeneration Nucleus pulposus Fibrinogen Vesicles Pyroptosis Fatty acid metabolism
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2590006424001406
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