Drug Interaction PBPK Modeling: Review of the Literature Exposes the Need for Increased Verification of Model Inputs and Outputs as Part of Credibility Assessment
ABSTRACT In vitro data are routinely used to support both static and physiologically based pharmacokinetic (PBPK) model‐based drug–drug interaction (DDI) predictions. Such efforts are possible after years of rapid progress, enabled by the greater availability of in vitro reagents, kinetic models, an...
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| Huvudupphov: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Wiley
2025-07-01
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| Serie: | Clinical and Translational Science |
| Ämnen: | |
| Länkar: | https://doi.org/10.1111/cts.70299 |
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