QR Code

APOE effects on regional tau in preclinical Alzheimer’s disease

Abstract Background APOE variants are strongly associated with abnormal amyloid aggregation and additional direct effects of APOE on tau aggregation are reported in animal and human cell models. The degree to which these effects are present in humans when individuals are clinically unimpaired (CU) b...

Full description

Saved in:
Main Authors: Christina B. Young, Emily Johns, Gabriel Kennedy, Michael E. Belloy, Philip S. Insel, Michael D. Greicius, Reisa A. Sperling, Keith A. Johnson, Kathleen L. Poston, Elizabeth C. Mormino, for the Alzheimer’s Disease Neuroimaging Initiative, the A4 Study Team
Format: Artigo
Language:Inglês
Published: BMC 2023-01-01
Series:Molecular Neurodegeneration
Subjects:
APOE
e2
e4
Amyloid
Tau
PET
Online Access:https://doi.org/10.1186/s13024-022-00590-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items