Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease

Abstract Background Dysfunction of glial cell communication is involved in Alzheimer’s disease (AD) pathogenesis, and the recent study reported that astrocytic secreted interleukin-3 (IL-3) participated in astrocyte–microglia crosstalk and restricted AD pathology in mice, but the effect of IL-3 on t...

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Hlavní autoři:	Zhi-Bo Wang, Ya-Hui Ma, Yan Sun, Lan Tan, Hui-Fu Wang, Jin-Tai Yu, for the Alzheimer’s Disease Neuroimaging Initiative
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2022-12-01
Edice:	Journal of Neuroinflammation
Témata:	Alzheimer’s disease Amyloid-β Interleukin-3 Tau Microglia Astrocyte
On-line přístup:	https://doi.org/10.1186/s12974-022-02679-5
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