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Modulation of ferroptosis via YY1-SLC7A11 axis in hepatic ischemia-reperfusion injury pathogenesis

YY1 is a crucial transcription factor and plays significant roles in biological processes. However, the mechanisms of YY1 action in ischemia-reperfusion injury and its regulatory role in ferroptosis have not been extensively studied. This study aims to elucidate the molecular mechanism by which NEDD...

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Autori principali: Wang Shaochuang, Jiang Baofei, Cao Jun, Xu Ting, Zhou Chengming, Yu Xiangyou, Wang Yi, Xie Yu, Ji Lindong, Zhou Guangrong, Wen Hao, Ma Long, Wu Kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: China Science Publishing & Media Ltd. 2025-07-01
Serie:Acta Biochimica et Biophysica Sinica
Soggetti:
NEDD4L
YY1
SLC7A11
ferroptosis
hepatic ischemia-reperfusion injury
ubiquitination
Accesso online:https://www.sciengine.com/doi/10.3724/abbs.2025093
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