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NEDD4L facilitates granulosa cell ferroptosis by promoting GPX4 ubiquitination and degradation

Background: Polycystic ovary syndrome (PCOS) is an androgen disorder and ovarian dysfunction disease in women of reproductive age. The cell death of granulosa cells (GCs) plays an important role in the development of PCOS. However, the mechanism of GC death is still unclear. Methods: In the curren...

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主要な著者: Hong Tang, Xiaomei Jiang, Yu Hua, Heyue Li, Chunlan Zhu, Xiaobai Hao, Minhui Yi, Linxia Li
フォーマット: Artigo
言語:Inglês
出版事項: Bioscientifica 2023-03-01
シリーズ:Endocrine Connections
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オンライン・アクセス:https://ec.bioscientifica.com/view/journals/ec/12/4/EC-22-0459.xml
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