Screening of Phenanthroquinolizidine Alkaloid Derivatives for Inducing Cell Death of L1210 Leukemia Cells with Negative and Positive P-glycoprotein Expression

We describe the screening of a set of cryptopleurine derivatives, namely thienoquinolizidine derivatives and (epi-)benzo analogs with bioactive phenanthroquinolizidine alkaloids that induce cytotoxic effects in the mouse lymphocytic leukemia cell line L1210. We used three variants of L1210 cells: i)...

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Autors principals:	Jana Kubíčková, Katarína Elefantová, Lucia Pavlikova, Martin Cagala, Mário Šereš, Peter Šafář, Štefan Marchalín, Kamila Ďurišová, Viera Boháčová, Zdena Sulova, Boris Lakatoš, Albert Breier, Petra Olejníková
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2019-06-01
Col·lecció:	Molecules
Matèries:	L1210 cells P-glycoprotein multidrug resistance phenanthroquinolizidine alkaloids apoptosis
Accés en línia:	https://www.mdpi.com/1420-3049/24/11/2127
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