miR-124 Inhibits Lung Tumorigenesis Induced by K-ras Mutation and NNK

Dysregulated miRNAs play important role in K-ras mutation or smoking caused lung tumorigenesis. Here, we investigate the role and mechanism of miR-124 in K-ras mutation or smoking-caused lung tumorigenesis and evaluate the therapeutic potential of miR-124 agomiR in K-ras mutation or smoking-caused l...

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Autors principals:	Hua Jin, Qing Li, Fenghao Cao, Shu-Nan Wang, Ren-Tao Wang, Yun Wang, Qun-You Tan, Cheng-Run Li, Hua Zou, Dong Wang, Cheng-Xiong Xu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2017-12-01
Col·lecció:	Molecular Therapy: Nucleic Acids
Matèries:	lung cancer miR-124 Akt activation NNK-induced lung cancer K-ras mutation-induced lung tumorigenesis
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S216225311730255X
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